A possible neural basis for autism: Oxytocin and Vasopressin expression

autism is a devastating developmental disorder which is one of five disorders that are termed Pervasive Developmental Disorder (PDD). autism is commonly associated with qualitative impairment in social interaction and communication as well as repetitive and stereotyped patterns of interest. These types of impairments may manifest themselves in the inability to form peer relationships, problems with verbal or nonverbal communication, and exhibition of repetitive motor mannerisms (Hollander et al. 2003). These debilitating symptoms have profound consequences when it comes to forming normal relationships. The anguish of autistic patients as well as their parents has served as motivation for current research of the underlying mechanisms behind autism. Much of this research has used such techniques as gene scanning, pharmacological and neurobiological approaches, yet the lack of concrete neurochemical, neurophysiological and neuroanatomical evidence leaves autism on the forefront of psychopathology (Insel et al. 1999