Gene Therapy

Type :

Presentation

Slides :

85 slides

Format :

.ppt

Published date :

07/20/2007

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Summary :

 
 

Table of Contents Gene Therapy Table of Contents

 
  1. The concept of gene therapy
  2. The clinical spectrum
  3. Gene delivery strategies
  4. The delivery vector
  5. Retroviral vectors
  6. Adenoviral vectors
  7. Adeno associated virus
  8. Selected disease applications
    1. Cystic fibrosis
    2. Hemophilia
    3. Myocardial and peripheral ischemia
    4. HIV infection and aids
  9. Replication competent viruses
  10. Recommendations
  11. Bibliography

Abstract

gene therapy is an experimental form of treatment whereby sequences of nucleic acids (i.e., genes) are delivered to cells to change their biologic function. The concept initially arose as replacement therapy for monogenic inherited disorders. For these disorders, the aim is to replace a defective gene with the normal counterpart. The delivered genetic material undergoes transcription and translation using the host cell's machinery, leading to in situ production of the normal protein and thereby correction of the phenotypic defect.

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About the author :

pencil image Raphael N.  
Level :General public Study : Medical studies School/University : UFMG

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