Gene Therapy
Summary :
Table of Contents
- The concept of gene therapy
- The clinical spectrum
- Gene delivery strategies
- The delivery vector
- Retroviral vectors
- Adenoviral vectors
- Adeno associated virus
- Selected disease applications
- Cystic fibrosis
- Hemophilia
- Myocardial and peripheral ischemia
- HIV infection and aids
- Replication competent viruses
- Recommendations
- Bibliography
Abstract
gene therapy is an experimental form of treatment whereby sequences of nucleic acids (i.e., genes) are delivered to cells to change their biologic function. The concept initially arose as replacement therapy for monogenic inherited disorders. For these disorders, the aim is to replace a defective gene with the normal counterpart. The delivered genetic material undergoes transcription and translation using the host cell's machinery, leading to in situ production of the normal protein and thereby correction of the phenotypic defect.
See similar documents : Medical studies
Latest in the category : Medical studies
3
An overview of digestive system in humans and digestive disorders
Term papers | 09/22/2009 | en | .doc | 8 pages
5
How can cardiac output be controlled physiologically and pharmacologically?
Term papers | 08/14/2009 | en | .doc | 7 pages
Most downloaded in the last 30 days : Medical studies
2
A medical case study concerning an elderly man with congestive heart failure
Term papers | 07/15/2009 | en | .doc | 7 pages
Change Currency
Our guarantee :
How it works?
Quality guaranteed
Refunds
Secure payment
Who are we ?
