Intrinsic asthma
Summary :
Table of Contents
- Introduction
- Allergen exposure
- The study of Tucson
- The study SAPALDIA
- Associated diseases
- Macrophage activation
- Conclusions and therapeutic perspectives
- Bibliography
Abstract
It is widely accepted that asthma is a clinical manifestation of atopy. Specially relevant in children, this concept is less obvious in adults where there is the classic distinction between asthma "extrinsic" (allergic) and "intrinsic" (non-allergic). intrinsic asthma is deliberately late third, a female is classic, as well as association with a naso-sinus polyposis, an intolerance to aspirin and lower corti-cosensibilité requiring more frequent to-corticothéra Oral pie. These patients have no history of allergy, skin tests are negative for aero-allergens and concentrations of serum total IgE and specific are low. The majority of published works often lignent however the existence of biological or clinical markers of inflammation-question "allergic" in a broad sense in asthma, even seemingly intrinsic.
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