LED syndrome antiphospholipide and CNS
Summary :
Table of Contents
- Summary
- Introduction
- Neuropsychiatric manifestations and LED
- Neurological manifestations of primary LED
- Psychiatric manifestations of lupus primary brain
- Diagnostic approach of neuropsychiatric manifestations of systemic lupus erythematosus
- Brain imaging
- Cytokines, polymorphisms and LED
- HLA and cytokines
- Conclusion
- Bibliography
Abstract
The neurolupus represents the second leading cause of death in the led. Although its incidence is high, it remains difficult to diagnose because of the diversity of events and the possible confusion with other brain diseases. In the absence of pathognomonic lesions, the diagnostic approach based on research criteria for an led, the distinction between functional or organic etiologies and the exclusion of symptoms unrelated to the led. The search for specific serological parameters, an analysis of the LCR, an EEG, a brain imaging psychomotor tests or brain biopsy, if necessary, will be carried out. If the cns lesions are associated with a syndrome antiphospholipide, treatment is based on anticoagulation otherwise immunosuppression should be considered
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