Pharmacodynamics of substance abuse
Summary :
Table of Contents
- General
- Introduction
- Addiction and psychological dependence
- Mechanisms
- Influences
- Awareness
- Therapeutic implications
- Tolerance and physical dependence
- Therapeutic implications
- Conclusion
- Bibliography
Abstract
abuse of pharmacologically active substances has attracted in recent decades numerous pharmacological studies, using a wide range of models and methods, and generating a considerable literature. Several reasons explain this trend: first, of course, the extent of the scourge, the severity of their individual and social, and finding effective treatments, but also the fact that this disorder is extraordinarily easy to reproduce in the 'animals, unlike many diseases affecting the psychiatric sphere. Hence the possibility of combining an infinite number of species studied, the modalities of experience, the products examined, the pre-treatment, stimuli, concurrent influences, tests and measures, to test hypotheses ever specified Correspondence and renewed fairly obvious between the laboratory and the clinic are on the whole a good relevance to all this research. In addition, finally the idea that this field of investigation explores a privileged interface between biology hard on one side and the other somewhat intangible psychological concepts such as motivations and emotions: the unveiling chemical substance behind our mental activities and emotions more elaborate, substance abuse awakens questioning our fundamental condition human.
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