Physiology of Pregnancy
Summary :
Table of Contents
- Maternal tissues of the fetal-maternal communication system
- The cardinal function of the uterus
- Overview of endometrial function
- The accommodation of pregnancy as the cardinal function of the endometrium/decidua
- Specialized functions of the decidua
- Estrogen action
- Progesterone action
- Bibliography
Abstract
Endometrium/decidua is the anatomical site of blastocyst apposition, implantation, and placental development. The endometrium is the mucosal lining of the uterine cavity and the decidua is the highly modified and specialized endometrium of pregnancy. From an evolutionary perspective, the human endometrium is highly developed in order to accommodate a hemochorioendothelial type of placentation. Endometrial development of a magnitude similar to that observed in women, that is with special spiral (or coiling) arteries, is restricted to only the catarrhine primates-such as humans, great apes, and Old World monkeys. Trophoblasts of the blastocyst invade these endometrial arteries during implantation and placentation to establish uteroplacental vessels.
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