Serotonin syndrome: A risk that should not be overlooked
Summary :
Table of Contents
- Introduction
- Clinical case
- History
- Epidemiology
- Metabolism and serotonin receptors
- Pathophysiology of serotonin syndrome
- Clinique
- Tests
- Risks with successive administration of antidepressants
- Miscellaneous
- Bibliography
Abstract
serotonin syndrome is a complication potentially lethal psychotropic. It is characterized by altered mental status and the presence of disorders neuro vegetative and neuromuscular. In most cases, this syndrome is secondary to the prescription of several drugs responsible for an increased rate of brain serotonin, but it may also occur in mono-therapy to the usual doses. The interruption of medicinal products in question and symptomatic treatment allow a favorable clinical course in most cases, but the prescription antagonists receiving of serotonin may be necessary. The sometimes fatal outcome illustrates the difficulty of recognizing this syndrome in the practice and its severity in the absence of early diagnosis.
Clinical case
A patient of 87 years, for a known hypertensive and vascular heart disease and a history of gradual weakening of intellectual and then a year, was admitted to hospital for urinary incontinence, apathy and their pain secondary to a fall without loss knowledge. An evaluation neuro psychiatrical highlighted a major depression and dementia with moderate frontal damage and memory impairment.
Clinical case
A patient of 87 years, for a known hypertensive and vascular heart disease and a history of gradual weakening of intellectual and then a year, was admitted to hospital for urinary incontinence, apathy and their pain secondary to a fall without loss knowledge. An evaluation neuro psychiatrical highlighted a major depression and dementia with moderate frontal damage and memory impairment.
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